Why Am I Always Tired? Research on Stress & Energy – IMMUNOSCIENCES

Intro

You sleep seven hours and wake up tired. By 4 pm, you are reaching for a second chai. Your blood test came back clean, so there is nothing "wrong". Yet you don't feel like yourself. If this sounds familiar, you are far from alone. Fatigue is one of the most common complaints doctors hear, and for many people no single cause ever shows up on a report.

Researchers have spent years on the space between "sick" and "feeling great". Three threads keep coming up: how your body handles stress, how your cells make energy, and how much everyday wear your cells are dealing with.

Signs your body is running on reserve

Waking up unrefreshed, even after a full night
An energy crash in the afternoon that coffee only half fixes
Feeling "on edge" or restless when you finally sit down
Finding it harder to focus than you used to

None of these alone means anything is wrong. But together they are a useful nudge to look at stress, sleep, and nutrition before they pile up.

What the research says (study cards)

What does study says	Study Ref	Summary	Ref
Ashwagandha and the stress hormone	2026 · Randomised, placebo-controlled · 141 adults · 8 weeks	Healthy adults aged 18 to 65 with moderate stress took an ashwagandha root extract or a placebo for eight weeks. The main measure was blood cortisol, the hormone that rises when you are under pressure. The researchers reported lower cortisol and better scores on standard stress and anxiety questionnaires in the ashwagandha groups, and described the extract as well tolerated. This adds to earlier Indian and Australian trials with similar findings.	1, 2, 3
CoQ10 and everyday tiredness	2022 · Meta-analysis · 13 trials · 1,126 people	CoQ10 is a compound your cells use to turn food into energy. Pooling 13 placebo-controlled trials, researchers found that CoQ10 reduced fatigue scores compared with placebo. Longer use and higher daily doses were linked to bigger effects, and the authors concluded it was safe in the doses studied.	4
Astaxanthin and oxidative stress	2010 · Randomised, double-blind · 42 young women · 8 weeks	Astaxanthin is the red-orange pigment found in algae and salmon. In healthy young women taking 2 or 8 mg a day, researchers measured lower levels of a marker of DNA oxidative damage and changes in several immune measures compared with placebo.	5

Pull quote

Each study tested one ingredient, at one dose, in one group of people. That is how good research works, and it is why we read it carefully rather than loudly.

More research

A few more pieces fill in the picture. Spirulina, a protein-rich blue-green alga, was studied in adults over 50 for 12 weeks, with researchers reporting improvements in blood and immune markers and calling for larger trials [6]. And curcumin from turmeric is famously hard for the body to absorb. A small 1998 study found that adding piperine, the active compound in black pepper, raised curcumin levels in the blood of healthy volunteers [7].

The basics come first

No capsule replaces the foundations. If you change one thing this week, start here.

Habit	Copy
Sleep	Keep the same wake-up time every day, weekends included. Your body clock likes routine more than extra hours.
Protein	Include dal, paneer, eggs, curd or sprouts in each main meal. Most Indian diets fall short here.
Movement	A 20-minute walk after lunch helps the afternoon slump more than a third coffee.
Daylight	Ten minutes of morning sunlight helps set your sleep-wake cycle.

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Formulas section

Eyebrow: From the Immunosciences lab

Heading: Two formulas built around this research

Intro: We formulate with the ingredients covered above and list every one on the label, with no proprietary blends. The studies tested single ingredients at their own doses. They did not test these products, so check the label and speak to our nutritionist about what suits you.

Advanced formula: Can Reset

Format line: 120 capsules · Day + Night · 30-day pack

Who it's for: For adults who want fuller, round-the-clock nutritional support. Two capsules a day, timed to your routine: one with breakfast, one after dinner.

Capsule	Ingredient	Short note	Dose
Day	Astaxanthin	Antioxidant carotenoid	see label
Day	CoQ10 (ubiquinol)	Cellular energy compound	see label
Day	Ashwagandha	Traditional adaptogen	see label
Day	DHA (omega-3)	Essential fatty acid	see label
Day	Passion flower · Annona reticulata	Traditional botanicals	see label
Night	Spirulina extract	Plant protein, phycocyanin	200 mg
Night	Resveratrol		100 mg
Night	Pomegranate extract		100 mg
Night	Sea buckthorn extract	Omega-7 fatty acids	90 mg
Night	Turmeric curcuminoids		50 mg
Night	Piperine	From black pepper	5 mg

Price: ₹12,832 (MRP ₹17,110, incl. taxes)

Shop Can Reset → product page · Ask a nutritionist → WhatsApp

Care formula: Health Reset

Format line: 60 capsules · Once daily · 30-day pack

Who it's for: A simpler daily routine with six plant-based ingredients. Two capsules each morning with water, before or after breakfast.

Ingredient	Short note	Dose
Ashwagandha	Traditional adaptogen	see label
Coenzyme Q10	Cellular energy compound	see label
Spirulina	Plant protein, phycocyanin	see label
Sea buckthorn	Omega-7 fatty acids	see label
Dandelion	Traditional botanical	see label
Graviola	Traditional botanical	see label

Price: ₹5,900 (incl. taxes)

Shop Health Reset → product page · Ask a nutritionist →

Note under both cards

Both are 100% plant-based nutraceuticals, made in WHO-GMP and ISO 22000 certified facilities, with every batch tested at NABL-accredited labs. Certificates of analysis are available on each product page.

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Heading: Not sure which one, or whether you need either?

Book a free 15-minute call with an Immunosciences nutritionist. We will look at your routine first, and only suggest a supplement if it makes sense for you.

Your diet, sleep and stress, reviewed
Checks against medicines you already take
A plan you can start this week

Book your consultation → WhatsApp +91 92895 83007 · Shop now → all products

References

A proprietary herbal extract of ashwagandha root for stress and anxiety in healthy adults: a randomized, double-blind, three-arm, placebo-controlled efficacy and safety study.
Journal of Medicine and Life. 2026;19(1):49–62. doi:10.25122/jml-2025-0172.
Salve J, Pate S, Debnath K, Langade D. Adaptogenic and anxiolytic effects of ashwagandha root extract in healthy adults. Cureus. 2019;11(12):e6466. PMID 32021735.
Lopresti AL, Smith SJ, Malvi H, Kodgule R. An investigation into the stress-relieving and pharmacological actions of an ashwagandha extract. Medicine. 2019;98(37):e17186.
Tsai IC, Hsu CW, Chang CH, Tseng PT, Chang KV. Effectiveness of coenzyme Q10 supplementation for reducing fatigue: a systematic review and meta-analysis. Frontiers in Pharmacology. 2022;13:883251.
Park JS, Chyun JH, Kim YK, Line LL, Chew BP. Astaxanthin decreased oxidative stress and inflammation and enhanced immune response in humans. Nutrition & Metabolism. 2010;7:18.
Selmi C, Leung PS, Fischer L, et al. The effects of Spirulina on anemia and immune function in senior citizens. Cellular & Molecular Immunology. 2011;8(3):248–254.
Shoba G, Joy D, Joseph T, Majeed M, Rajendran R, Srinivas PS. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Medica. 1998;64(4):353–356. PMID 9619120.

Footer disclaimer

Health supplement. Not for medicinal use. These products are not intended to diagnose, treat, cure or prevent any disease. Individual results vary.

This article is for general information and does not replace advice from your doctor. The studies cited tested individual ingredients, often at doses different from those in our products, and do not test Can Reset or Health Reset themselves. If you are pregnant, breastfeeding, under 18, on regular medication (including blood thinners, thyroid or diabetes medicines) or have a medical condition, consult your doctor before use.